001×2
001×2 is a gel-type strong acid cation exchange resin on a polystyrene-divinylbenzene matrix, bearing sulfonic acid groups (–SO₃H) — the solid equivalent of sulfuric acid. Its very low crosslinking leaves little steric hindrance for molecules moving inside the bead, making it suitable for extracting macromolecular antibiotics carrying multiple positive charges.
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Product Introduction
001×2 is a gel-type strong acid cation exchange resin on a polystyrene-divinylbenzene matrix, bearing sulfonic acid groups (–SO₃H) — the solid equivalent of sulfuric acid. Its very low crosslinking leaves little steric hindrance for molecules moving inside the bead, making it suitable for extracting macromolecular antibiotics carrying multiple positive charges.
International Equivalents
Dowex 50×2
Typical Physical & Chemical Properties
| Appearance | Pale yellow translucent beads |
|---|---|
| Functional group | -SO3H |
| Total exchange capacity | ≥4.5mmol/g |
| Volumetric exchange capacity | ≥0.6mmol/ml |
| Moisture content | 75%~80% |
| True density (wet) | 1.05~1.12g/ml |
| Bulk density (wet) | 0.72~0.82g/ml |
| Particle size range | 0.315~1.25mm |
| Effective particle size | 0.40-0.70mm |
| Uniformity coefficient | ≤1.6 |
| Max. service temperature | Na120 °C |
| Whole bead rate after attrition | ≥85% |
| Max. operating temperature | 120 ℃ |
| Resin bed height | 1~3m |
| Service flow rate | 2~10BV/h |
| Backwash flow rate | 4~10BV/h |
| Regeneration (elution) flow rate | 1~2BV/h |
| Regenerant dosage | 2 BV 3~5% HCl, 2 BV 2~4% NaOH |
Handling, Storage & Loading Notes
- Transport & storage. Store the resin in its wet state, preferably above 0 °C. For long idle periods, keep the container closed or add brine of ≥5% NaCl. Protect from freezing during transport, and do not stack heavy objects on top of the resin to avoid crushing the beads.
- Pre-treatment. For general requirements, one alkaline → water → acid → water cycle is sufficient; for strict requirements, perform three cycles and finish with the required ionic form.
- Loading. Allow for the swelling on form conversion and leave enough freeboard to prevent overflow while keeping a proper liquid level. Keep the column aspect ratio in a reasonable range to avoid channeling. Load wet or backwash to remove air bubbles from the bed.
- Feed quality. Before entering the resin column, the liquid should be coagulated, filtered or sand-filtered to ensure it is free of suspended solids that could clog the resin pores.
- Idle columns. Resin left idle in a column for a long time must be washed out and stored clean, or kept submerged in brine; it must never dehydrate. Backwash from time to time to loosen the bed and prevent caking.